Significats de dorsal horn en anglès

Activity of dorsal horn neurons, in turn, enhances activation of spinal glia.

Chronic morphine treatment significantly increased levels of D2DR in mice spinal dorsal horn.

In contrast, nNOS staining in dorsal horn neurons was unaltered by these manipulations.

They were distributed in the whole dorsal horn, especially in the superficial dorsal horn.

Wnt1 was also increased in activated astrocytes in the dorsal horn after spinal nerve ligation.

Immunostaining for their phosphorylated counterparts was very low or undetectable in DRG and dorsal horn.

ACE2 was expressed in neurons and microglia but absent from astrocytes in the superficial dorsal horn.

Stimulation of the superior sagittal sinus resulted in activation of cells in the dorsal horn of C2.

Conclusion: Incision-induced NRG1 expression mediated activation of dorsal horn microglia and contributed to the development of mechanical allodynia.

Thus, a physiological role for ATP may be as a neuronal-glial signaling molecule within the spinal dorsal horn.

Peripheral axotomy did not clearly affect Scgn expression in DRGs, dorsal horn or ventral horn neurons in mouse.

Conclusions: Our results suggest that ERK activation in the spinal dorsal horn plays a vital role in NP-evoked hyperalgesia.

It provides one of the major sources of noradrenaline to the dorsal horn of the spinal cord and neocortex.

Analgesia seems to be mediated mainly by activation of alpha2 adrenoceptors in the dorsal horn of the spinal cord.

Spinal GBP also significantly inhibited dorsal horn wide-dynamic-range neuronal responses to a range of evoked stimuli in SNL rats.

Noxious stimuli are sensed and carried to the spinal cord dorsal horn by A delta and C primary afferent fibers.